Glycolysis
During catabolism, only about 40% of the energy available from oxidizing glucose is used to synthesize ATP. Remaining 60%

is used to reduce NADP
is lost as heat
is stored as fat.
remains in the products of metabolism

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Glycolysis
Why does the glycolytic pathway continue in the direction of glucose catabolism?

There are essentially three irreversible reactions that act as the driving force for the pathway
Glycolysis occurs in either direction
High levels of ATP keep the pathway going in a forward direction
The enzymes of glycolysis only function in one direction

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