DNA Replication
Proofreading activity to maintain the fidelity of DNA synthesis

occurs after the synthesis has been completed
is a function of the 3'-5' exonuclease activity of the DNA polymerases
occurs in prokaryotes but not eukaryotes
requires the presence of an enzyme separate from the DNA polymerases

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DNA Replication
The replication of chromosomes by eukaryotes occurs in a relatively short period of time because

the eukaryotes have more amount of DNA for replication
each chromosome contains multiple replicons
the eukaryotic replication machinery is 1000 times faster than the prokaryotes
eukaryotic DNA is always single stranded

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