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ANTIMICROBIAL CHEMOTHERAPEUTIC AGENTS

Antimicrobial Chemotherapeutic Agents
The antibiotics not having good activity against Enterobacteriaceae is

trimethoprim-sulphamethoxazole
clindamycin
ciprofloxacin
cefoxitin

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Antimicrobial Chemotherapeutic Agents
Quinones and related antibiotics are

actinorhodin
tetracyclines
mitomycin
all of these

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Antimicrobial Chemotherapeutic Agents
Both penicillin and fluoroquinolones

bind to and inactivate a bacterial protein
inhibit the cross-linking of peptidoglycan
are inactivated by β-lactamase
must be transported into the cytoplasm in order to act

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Antimicrobial Chemotherapeutic Agents
A broad-spectrum antibiotic such as chloramphenicol is one that

kills both Gram positive and Gram negative bacteria
kills all microorganisms
kills numerous types of microbes
kills all bacteria

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Antimicrobial Chemotherapeutic Agents
Vancomycin inhibits peptidoglycan synthesis by binding

D-alanyl - D-alanine synthetase
D-alanyl - D-alanine
alanine racemase
amidase

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