DNA Structure and Replication
An important difference between eukaryotic and prokaryotic DNA replication is

multiple origins of replication in eukaryotes
eukaryotic DNA polymerases are faster
RNA primers are not required in eukaryotes
more DNA polymerases are found in eukaryotes

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DNA Structure and Replication
In DNA, nucleotides are covalently joined together by

3', 4' phosphodiester bonds to form a repetitive sugar-phosphate chain
2', 5' phosphodiester bonds to form a repetitive sugar-phosphate chain
2', 3' phosphodiester bonds to form a repetitive sugar-phosphate chain
3', 5' phosphodiester bonds to form a repetitive sugar-phosphate chain

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