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Antimicrobial Chemotherapeutic Agents

Antimicrobial Chemotherapeutic Agents
Amphotericin B and polymyxin interfere with

DNA function
cell wall synthesis
protein synthesis
cell membrane function

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Antimicrobial Chemotherapeutic Agents
The larger the __________ , the better the chemotherapeutic agent.

therapeutic index
spectrum
selective toxicity
therapeutic dose

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Antimicrobial Chemotherapeutic Agents
Which of the following drugs may show plasmid-mediated resistance?

Nalidixic acid
Rifampicin
Methicillin
Ampicillin

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Antimicrobial Chemotherapeutic Agents
The most selective antibiotics are those that interfere with the synthesis of

bacterial plasma membrane
bacterial DNA
bacterial cell walls
bacterial RNA

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Antimicrobial Chemotherapeutic Agents
Which of the following tests is used to determine the minimal lethal concentration?

Broth dilution test
All of these
Agar dilution test
Dilution susceptibility tests

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Antimicrobial Chemotherapeutic Agents
The penicillin stable in gastric acid and suitable for oral administration is

carbenicillin
methicillin
pencillin-G
closacillin

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